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Literature summary for 3.4.22.2 extracted from

  • Franco, O.L.; Grossi de Sa, M.F.; Sales, M.P.; Mello, L.V.; Oliveira, A.S.; Rigden, D.J.
    Overlapping binding sites for trypsin and papain on a Kunitz-type proteinase inhibitor from Prosopis juliflora (2002), Proteins Struct. Funct. Genet., 49, 335-341.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
E64 0.025 mg/ml, 65% inhibition Carica papaya
Kunitz type trypsin inhibitor i.e. PTPKI, SwissProt: P32722 (alpha chain), P32773 (beta-chain), a small Kunitz trypsin inhibitor from Prosopis juliflora, 0.025 mg/ml, 98.3% inhibition, overlapping binding sites for trypsin and papain Carica papaya

Organism

Organism UniProt Comment Textmining
Carica papaya
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Phe-Arg-4-methylcoumaryl-7-amide + H2O
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Carica papaya ?
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?