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BRENDA support

Literature summary for 3.4.22.15 extracted from

  • Fei, X.F.; Qin, Z.H.; Xiang, B.; Li, L.Y.; Han, F.; Fukunaga, K.; Liang, Z.Q.
    Olomoucine inhibits cathepsin L nuclear translocation, activates autophagy and attenuates toxicity of 6-hydroxydopamine (2009), Brain Res., 1264, 85-97.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
Rattus norvegicus 5634
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neuron
-
Rattus norvegicus
-

Expression

Organism Comment Expression
Rattus norvegicus pretreatment of rats or primary DA neurons with 200 nM olomoucine results in a partial blockade of nuclear translocation of cathepsin L after 12 h 0.008 mg 6-hydroxydopamine exposure down
Rattus norvegicus increased immunoreactivities of cathepsin L is seen in the impaired substantia nigra after 12 h 0.008 mg 6-hydroxydopamine treatment up