Literature summary for 3.4.22.15 extracted from

Benbrahim-Tallaa, L.; Siddeek, B.; Bozec, A.; Tronchon, V.; Florin, A.; Friry, C.; Tabone, E.; Mauduit, C.; Benahmed, M.
Alterations of Sertoli cell activity in the long-term testicular germ cell death process induced by fetal androgen disruption (2008), J. Endocrinol., 196, 21-31.

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
Sertoli cell	cells originating from 15-day-old rats treated in utero with the anti-androgen flutamide do no longer protect adult germ cells against apoptosis. Untreated spermatocytes or spermatids exhibit increased active caspase-3 levels when co-cultured with Sertoli cells isolated from rat testes exposed in utero to the anti-androgen	Rattus norvegicus	-
testis	adult testes exposed in utero to anti-androgens display decreased levels of several genes mainly expressed in adult Sertoli cells such as anti-Mullerian hormone receptor type II, Cox-1, cyclin D2, cathepsin L, and GSTalpha	Rattus norvegicus	-

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Release 2023.1 (January 2023)