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Literature summary for 3.4.22.15 extracted from
- Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease (2007), J. Clin. Invest., 117, 2095-2104.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | cell treatment with lipopolysaccharids induces expression of cytoplasmic CatL | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Mus musculus | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| benzyloxycarbonyl-Phe-Phe-fluoromethyl ketone | - |
Homo sapiens |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Homo sapiens | 5737 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 30000 | - |
SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P07711 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CV-(L-Phe-Arg)2 + H2O | - |
Homo sapiens | ? | - |
? | |
| dynamin + H2O | CatL is highly reactive toward recombinant dynamin at pH 5.0 and 6.0 | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CatL | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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