Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.15 extracted from

  • Kooistra, T.; Millard, P.C.; Lloyd, J.B.
    Role of thiols in degradation of proteins by cathepsins (1982), Biochem. J., 204, 471-477.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
2-mercaptoethanol strong activation of hydrolysis of insulin or albumin, at pH 4.0 and at pH 5.5 Rattus norvegicus
Cys strong activation of hydrolysis of insulin or albumin, at pH 4.0 and at pH 5.5 Rattus norvegicus
cysteamine strong activation of hydrolysis of insulin or albumin, at pH 4.0 and at pH 5.5 Rattus norvegicus
dithiothreitol strong activation of hydrolysis of insulin or albumin, at pH 4.0 and at pH 5.5 Rattus norvegicus
glutathione strong activation of hydrolysis of insulin or albumin, at pH 4.0 and at pH 5.5 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Albumin + H2O
-
Rattus norvegicus ?
-
?
insulin + H2O
-
Rattus norvegicus ?
-
?