Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzyloxycarbonyl-Phe-Ala-CNH2 | - |
Rattus norvegicus | |
Benzyloxycarbonyl-Phe-Phe-CHN2 | - |
Rattus norvegicus | |
diazomethanes | irreversible inhibition of hydrolysis of leucine enkephalin | Rattus norvegicus | |
leupeptin | reversible inhibition of hydrolysis of leucine enkephalin | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00125 | - |
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide | - |
Rattus norvegicus | |
0.0208 | - |
Leu-Trp-Met-Arg-Phe-Ala | - |
Rattus norvegicus | |
0.0825 | - |
leucine enkephalin | - |
Rattus norvegicus | |
0.1096 | - |
methionine enkephalin-Arg-Phe | - |
Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
34900 | - |
gel filtration | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide + H2O | - |
Rattus norvegicus | ? | - |
? | |
Leu-Trp-Met-Arg-Phe-Ala + H2O | - |
Rattus norvegicus | Leu-Trp-Met + Arg-Phe-Ala | - |
? | |
methionine enkephalin-Arg-Phe + H2O | - |
Rattus norvegicus | ? | - |
? | |
Tyr-Gly-Gly-Phe-Leu + H2O | - |
Rattus norvegicus | Tyr-Gly + Gly-Phe-Leu | - |
? | |
Tyr-Gly-Gly-Phe-Leu-Arg + H2O | - |
Rattus norvegicus | Tyr-Gly + Gly-Phe-Leu-Arg | - |
? | |
Tyr-Gly-Gly-Phe-Leu-Arg-Arg + H2O | - |
Rattus norvegicus | Tyr-Gly + Gly-Phe-Leu-Arg-Arg | - |
? | |
Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile + H2O | - |
Rattus norvegicus | Tyr-Gly + Gly-Phe-Leu-Arg-Arg-Ile | - |
? | |
Tyr-Gly-Gly-Phe-Met + H2O | - |
Rattus norvegicus | Tyr-Gly + Gly-Phe-Met | - |
? | |
Tyr-Gly-Gly-Phe-Met-Arg-Arg + H2O | - |
Rattus norvegicus | Tyr-Gly + Gly-Phe-Met-Arg-Arg | - |
? | |
Tyr-Gly-Gly-Phe-Met-Arg-Gly-Leu + H2O | cleavage sites Gly-Gly and Met-Arg | Rattus norvegicus | ? | - |
? | |
Tyr-Gly-Gly-Phe-Met-Arg-Phe + H2O | cleavage sites: Gly-Gly and Met-Arg | Rattus norvegicus | ? | - |
? | |
Tyr-Gly-Gly-Phe-Met-Arg-Phe-NH2 + H2O | cleavage sites Gly-Gly and Met-Arg | Rattus norvegicus | ? | - |
? | |
Tyr-Gly-Gly-Phe-Met-NH2 + H2O | - |
Rattus norvegicus | Tyr-Gly + Gly-Phe-Met-NH2 | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
5.53 | - |
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide | - |
Rattus norvegicus | |
26.6 | - |
Leu-Trp-Met-Arg-Phe-Ala | - |
Rattus norvegicus | |
33.9 | - |
leucine enkephalin | - |
Rattus norvegicus | |
43.2 | - |
methionine enkephalin-Arg-Phe | - |
Rattus norvegicus |