Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dermatan | - |
Homo sapiens | |
heparin | - |
Homo sapiens | |
additional information | no significant effect on enzyme activity by chondroitin | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
citrate | - |
Homo sapiens | |
additional information | no significant effect on enzyme activity by chondroitin | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y337 | gene KLK5 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Abz-APGRVVGGA-Q-N-[2,4-dinitrophenyl]-ethylenediamine + H2O | - |
Homo sapiens | ? | - |
? | |
human plasminogen + H2O | generation of a 29 kDa fragment | Homo sapiens | human plasmin + ? | - |
? | |
additional information | no activity with peptides CPGRVVGGC, and QVEPKKCPGRVVGGCVAHPHS | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
KLK5 | - |
Homo sapiens |
tissue kallikrein 5 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | the enzyme is upregulated in some types of cancers, mainly prostate and ovarian cancers | up |