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Literature summary for 3.4.21.B39 extracted from
- SPINK9: A selective, skin-specific Kazal-type serine protease inhibitor (2009), J. Invest. Dermatol., 129, 1656-1665.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| SPINK9 | i.e. serine protease inhibitor Kazal type 9, KLK5-specific inhibitor, KLK5 degradation of fibrinogen was totally inhibited by SPINK9 | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | KLK5 plays a central role in skin desquamation as an initiating activating enzyme in proteolytic cascades formed by kallikreins | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Fibrinogen + H2O | - |
Homo sapiens | ? | - |
? | |
| additional information | KLK5 plays a central role in skin desquamation as an initiating activating enzyme in proteolytic cascades formed by kallikreins | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| KLK5 | - |
Homo sapiens |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.000065 | - |
serine protease inhibitor Kazal type 9 | - |
Homo sapiens |
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