Literature summary for 3.4.21.B27 extracted from

Declercq, J.; Ramos-Molina, B.; Sannerud, R.; Brouwers, B.; Pruniau, V.P.E.G.; Meulemans, S.; Plets, E.; Annaert, W.; Creemers, J.W.M.
Endosome to trans-Golgi network transport of Proprotein Convertase 7 is mediated by a cluster of basic amino acids and palmitoylated cysteines (2017), Eur. J. Cell Biol., 96, 432-439 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
plasma membrane	the enzyme is concentrated in the trans-Golgi network but it shuttles between the plasma membrane and the trans-Golgi network depending on sequences in the cytoplasmic tail. A short region containing a three amino acids motif, P724-L725-C726, is essential and sufficient for internalization of PC7 but not for trans-Golgi network localization, which requires the additional presence of the juxtamembrane region. Endosome to trans-Golgi network transport of proprotein convertase 7 is mediated by a cluster of basic amino acids and palmitoylated cysteinesA motif	Rattus norvegicus	5886	-
trans-Golgi network	the enzyme is concentrated in the trans-Golgi network but it shuttles between the plasma membrane and the trans-Golgi network depending on sequences in the cytoplasmic tail. A short region containing a three amino acids motif, P724-L725-C726, is essential and sufficient for internalization of PC7 but not for trans-Golgi network localization, which requires the additional presence of the juxtamembrane region	Rattus norvegicus	5802	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	Q62849	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
NRK cell	-	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
PC7	-	Rattus norvegicus

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Release 2023.1 (January 2023)