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Literature summary for 3.4.21.94 extracted from

  • Zhan, S.; Zhou, A.; Piper, C.; Yang, T.
    Dynamic changes in proprotein convertase 2 activity in cortical neurons after ischemia/reperfusion and oxygen-glucose deprivation (2013), Neural Regen. Res., 8, 83-89.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine in a rat model of transient focal cerebral ischemia by performing 100 min of middle cerebral artery occlusion, proprotein convertase 2 activity gradually decreases in the ischemic cortex with increasing duration of reperfusion. In an in vitro model of experimental oxygen-glucose deprivation using cultured rat cortical neuron, the number of terminal deoxynucleotidyl transferase-mediated 2'-deoxyuridine 5'-triphosphate-biotin nick end labeling-positive neurons significantly increases and proprotein convertase 2 activity also decreases gradually with increasing duration of oxygen-glucose deprivation Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P28841
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