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Literature summary for 3.4.21.93 extracted from

  • Henrich, S.; Lindberg, I.; Bode, W.; Than, M.E.
    Proprotein convertase models based on the crystal structures of furin and kexin: explanation of their specificity (2004), J. Mol. Biol., 345, 211-227.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Reaction

Reaction Comment Organism Reaction ID
release of protein hormones, neuropeptides and renin from their precursors, generally by hydrolysis of -Lys-Arg-/- bonds active site and substrate binding structure, enzyme-substrate interactions at prime and non-prime subsites Homo sapiens

Subunits

Subunits Comment Organism
More amino acid sequence alignment of soluble ectodomain and active site cleft, domain structures, enzyme structure modeling based on the crystal structures of furin and kexin, overview Homo sapiens

Synonyms

Synonyms Comment Organism
PC1
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Homo sapiens