Literature summary for 3.4.21.73 extracted from

Kowal, K.; Zukowski, S.; Moniuszko, M.; Bodzenta-?ukaszyk, A.
Plasminogen activator inhibitor-1 (PAI-1) and urokinase plasminogen activator (uPA) in sputum of allergic asthma patients (2008), Folia Histochem. Cytobiol., 46, 193-198.

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Application

Application	Comment	Organism
medicine	in sputum derived from patients with house dust mite allergic asthma, the medium concentration of uPA is significantly greater than in healthy control patients. The sputum concentration of uPA correlates with sputum total cell count and with logarithmically transformed exhaled nitric oxide concentration, but not with FEV1 or bronchial reactivity to histamine. Tge effect of uPA seems to be independent of its fibrinolytic activity	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	patients with allergic asthma	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
sputum	in sputum derived from patients with house dust mite allergic asthma, the medium concentration of uPA is significantly greater than in healthy control patients. The sputum concentration of uPA correlates with sputum total cell count and with logarithmically transformed exhaled nitric oxide concentration, but not with FEV1 or bronchial reactivity to histamine. Tge effect of uPA seems to be independent of its fibrinolytic activity	Homo sapiens	-

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Release 2023.1 (January 2023)