Literature summary for 3.4.21.73 extracted from

Fevang, B.; Eugen-Olsen, J.; Yndestad, A.; Brosstad, F.; Beiske, K.; Aukrust, P.; Froland, S.S.
Enhanced levels of urokinase plasminogen activator and its soluble receptor in common variable immunodeficiency (2009), Clin. Immunol., 131, 438-446.

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Application

Application	Comment	Organism
medicine	all patients examined with common variable immunodeficiency had increased plasma levels of soluble uPA receptor with particularly high levels in those with splenomegaly and thrombocytopenia. Plasma uPA levels were also raised in these patients, and both soluble uPA receptor and uPA levels correlated with the monocyte activation marker neopterin. Monocytes from patients with common variable immunodeficiency had increased expression of uPA receptor	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	patients with common variable immunodeficiency	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood plasma	patients with common variable immunodeficiency show increased levels of plasma uPA	Homo sapiens	-

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Release 2023.1 (January 2023)