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Literature summary for 3.4.21.73 extracted from
- Pro-urokinase up-regulates the expression of urokinase-type plasminogen activator (u-PA) in human pulmonary arterial endothelial cells (2008), Thromb. Res., 121, 485-491.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | pro-urokinase upregulates the expression of urokinase-type plasminogen activator in pulmonary arterial endothelial cells, but not the expression level of the uPA receptor | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | uPA interacts with the uPA receptor, which is important for many of the enzyme's biological functions | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| endothelial cell | pulmonary arterial | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | uPA interacts with the uPA receptor, which is important for many of the enzyme's biological functions | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| u-PA | - |
Homo sapiens |
| Urokinase-type plasminogen activator | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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