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Literature summary for 3.4.21.73 extracted from

  • Bryer, S.C.; Fantuzzi, G.; Van Rooijen, N.; Koh, T.J.
    Urokinase-type plasminogen activator plays essential roles in macrophage chemotaxis and skeletal muscle regeneration (2008), J. Immunol., 180, 1179-1188.
    View publication on PubMed
Search for more literature for 3.4.21.73

Protein Variants

Protein Variants Comment Organism
additional information enzyme-deficient mice show decreased accumulation of macrophages following muscle injury and severely impaired muscle regeneration, overview Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus urokinase-type plasminogen activator plays essential roles in skeletal muscle regeneration and healing, macrophage depletion leads to impaired muscle regeneration, molecular mechanism, overview, the macrophage enzyme is essentially required for chemotaxis, mechanism independent of receptor binding, overview ?
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additional information Mus musculus C57BL/6 urokinase-type plasminogen activator plays essential roles in skeletal muscle regeneration and healing, macrophage depletion leads to impaired muscle regeneration, molecular mechanism, overview, the macrophage enzyme is essentially required for chemotaxis, mechanism independent of receptor binding, overview ?
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Organism

Organism UniProt Comment Textmining
Mus musculus
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 C57BL/6 mice
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Mus musculus C57BL/6
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 C57BL/6 mice
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Source Tissue

Source Tissue Comment Organism Textmining
macrophage
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 Mus musculus
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skeletal muscle
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 Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information urokinase-type plasminogen activator plays essential roles in skeletal muscle regeneration and healing, macrophage depletion leads to impaired muscle regeneration, molecular mechanism, overview, the macrophage enzyme is essentially required for chemotaxis, mechanism independent of receptor binding, overview Mus musculus ?
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 ?
additional information urokinase-type plasminogen activator plays essential roles in skeletal muscle regeneration and healing, macrophage depletion leads to impaired muscle regeneration, molecular mechanism, overview, the macrophage enzyme is essentially required for chemotaxis, mechanism independent of receptor binding, overview Mus musculus C57BL/6 ?
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 ?

Synonyms

Synonyms Comment Organism
uPA
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 Mus musculus
Urokinase-type plasminogen activator
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 Mus musculus