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Literature summary for 3.4.21.73 extracted from

  • Chu, S.C.; Yang, S.F.; Lue, K.H.; Hsieh, Y.S.; Li, T.J.; Lu, K.H.
    Naproxen, meloxicam and methylprednisolone inhibit urokinase plasminogen activator and inhibitor and gelatinases expression during the early stage of osteoarthritis (2008), Clin. Chim. Acta, 387, 90-96.
    View publication on PubMed
Search for more literature for 3.4.21.73

Inhibitors

Inhibitors Comment Organism Structure
meloxicam reduces enzyme secretion in chondral and synovial cultures downregulating the PA/plasmin system Homo sapiens
methylprednisolone reduces enzyme secretion in chondral and synovial cultures downregulating the PA/plasmin system Homo sapiens
naproxen reduces enzyme secretion in chondral and synovial cultures downregulating the PA/plasmin system Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cartilage
-
 Homo sapiens
-
knee
-
 Homo sapiens
-
meniscus
-
 Homo sapiens
-
synovium
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 enzyme activity in different tissues with and without inhibitor treatment, overview Homo sapiens

Synonyms

Synonyms Comment Organism
uPA
-
 Homo sapiens
Urokinase plasminogen activator
-
 Homo sapiens
urokinase-type PA
-
 Homo sapiens