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Literature summary for 3.4.21.73 extracted from

  • Kim, T.D.; Song, K.S.; Li, G.; Choi, H.; Park, H.D.; Lim, K.; Hwang, B.D.; Yoon, W.H.
    Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer (2006), BMC Cancer, 6, 211.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.73

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 x * 55000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme is involved in colorectal cancer invasion and metastasis ?
-
 ?
plasminogen + H2O Homo sapiens
-
 plasmin + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colon very low enzyme content Homo sapiens
-
colonic carcinoma cell
-
 Homo sapiens
-
colorectal cancer cell
-
 Homo sapiens
-
additional information uPA is expressed differentially in colon and rectal cancers, expression analysis, overview Homo sapiens
-
rectal carcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is involved in colorectal cancer invasion and metastasis Homo sapiens ?
-
 ?
plasminogen + H2O
-
 Homo sapiens plasmin + ?
-
 ?

Subunits

Subunits Comment Organism
? x * 55000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
uPA
-
 Homo sapiens
Urokinase-type plasminogen activator
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Homo sapiens