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Literature summary for 3.4.21.73 extracted from
- Kinetic analysis of plasminogen activator inhibitor type-2: urokinase complex formation and subsequent internalization by carcinoma cell lines (2004), Exp. Cell Res., 297, 259-271.
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | assay of cellular internalization and localization of enzyme:PAI-2 inhibitor complex based on the use of inhibitor labelled with Alexa488 fluorochrome and a polyclonal antibody | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| PAI-2 | i.e. plasminogen activator inhibitor type 2, cell-surface enzyme:PAI-2 complex formation is reflective of complete enzyme inhibition, kinetic analysis of inhibition | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| MCF-7 cell | breast cancer cell | Homo sapiens | - |
| MDA-MB-231 cell | breast cancer cell | Homo sapiens | - |
| PC-3 cell | - |
Homo sapiens | - |
| T-47D cell | breast cancer cell | Homo sapiens | - |
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Release 2023.1 (January 2023)
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