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Literature summary for 3.4.21.73 extracted from

  • Cui, Z.h.; Yang, T.; Gao, Q.g.; Wang, Y.
    Urokinase plasminogen activator (uPA) is a positive regulator of outer root sheath keratinocyte proliferation (2004), Cell Biol. Int., 28, 571-575.
    View publication on PubMed
Search for more literature for 3.4.21.73

Inhibitors

Inhibitors Comment Organism Structure
amiloride significant reduction of hair follicle keratinocyte proliferation Mus musculus
enzyme-specific antibody significant reduction of hair follicle keratinocyte proliferation Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus enzyme protein is consistently elevated in the hyperproliferative hair follicle keratinocyte, and inhibiton of enzyme decreases hair follicle keratinocyte proliferation ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
epidermis outer root sheath keratinocyte of vibrissa follicle Mus musculus
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hair follicle outer root sheath keratinocyte of vibrissa follicle Mus musculus
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keratinocyte outer root sheath keratinocyte of vibrissa follicle Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme protein is consistently elevated in the hyperproliferative hair follicle keratinocyte, and inhibiton of enzyme decreases hair follicle keratinocyte proliferation Mus musculus ?
-
 ?