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Literature summary for 3.4.21.69 extracted from

  • Nold, M.F.; Nold-Petry, C.A.; Fischer, D.; Richter, B.; Blaheta, R.; Pfeilschifter, J.; Muhl, H.; Schranz, D.; Veldman, A.
    Activated protein C downregulates p38 mitogen-activated protein kinase and improves clinical parameters in an in-vivo model of septic shock (2007), Thromb. Haemost., 98, 1118-1126.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Sus scrofa activated protein C downregulates p38 mitogen-activated protein kinase p53 and improves clinical parameters in an in-vivo model of septic shock, overview ?
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?
additional information Homo sapiens activated protein C downregulates p38 mitogen-activated protein kinase p53 and improves clinical parameters in an in-vivo model of septic shock, overview, the activated enzyme prevents acidosis and tends to improve heart rate responses to endotoxia ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Sus scrofa
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German Landrace piglets
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Sus scrofa
-
umbilical vein endothelial cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information activated protein C downregulates p38 mitogen-activated protein kinase p53 and improves clinical parameters in an in-vivo model of septic shock, overview Sus scrofa ?
-
?
additional information activated protein C downregulates p38 mitogen-activated protein kinase p53 and improves clinical parameters in an in-vivo model of septic shock, overview, the activated enzyme prevents acidosis and tends to improve heart rate responses to endotoxia Homo sapiens ?
-
?