Protein Variants | Comment | Organism |
---|---|---|
additional information | replacement of autolysis loop of protein by the corresponding loop of factor X. Mutant is activated by thrombin with 5fold higher rate in presence of Ca2+, Ca2+-affinity of mutant is impaired 3fold and anticoagulation function of mutant is improved 4-5fold in the absence, but not in the presence of protein S. Plasma half-life of mutant is markedly shortened | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |