Protein Variants | Comment | Organism |
---|---|---|
additional information | enzyme variant with seven point-mutations in Gla domain, enhanced affinity for negatively charged phospholipid and increased anticoagulantic potential. Degradation of Factor Va yields similar fragments from wild-type and mutant, mutant is more efficient in absence and presence of protein S | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Factor Va + H2O | hydrolysis at Arg506 and Arg 306 | Homo sapiens | ? | - |
? |