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Literature summary for 3.4.21.68 extracted from

  • McBane, R.D.; Hardison, R.M.; Sobel, B.E.; Sobel, B.E.
    Comparison of plasminogen activator inhibitor-1, tissue type plasminogen activator antigen, fibrinogen, and D-dimer levels in various age decades in patients with type 2 diabetes mellitus and stable coronary artery disease (from the BARI 2D trial) (2010), Am. J. Cardiol., 105, 17-24.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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the plasminogen activator inhibitor-1 antigen and its activity and their ratios to tissue-type plasminogen activator are all paradoxically lower with advancing age in patients with type 2 diabetes mellitus, t-PA is significantly and directly associated with increasing age Homo sapiens

Synonyms

Synonyms Comment Organism
t-PA
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Homo sapiens
t-plasminogen activator
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Homo sapiens
Tissue-type plasminogen activator
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Homo sapiens

General Information

General Information Comment Organism
malfunction the concentrations of t-PA and PAI-1 in the plasma have been identified as variables contributing to the risk of arterial thrombosis Homo sapiens