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BRENDA support

Literature summary for 3.4.21.68 extracted from

  • Onder, A.M.; Chandar, J.; Simon, N.; Diaz, R.; Nwobi, O.; Abitbol, C.L.; Zilleruelo, G.
    Comparison of tissue plasminogen activator-antibiotic locks with heparin-antibiotic locks in children with catheter-related bacteraemia (2008), Nephrol. Dial. Transplant., 23, 2604-2610.
    View publication on PubMed

Application

Application Comment Organism
drug development both TPA-antibiotic locks and heparin-antibiotic locks used in conjunction with systemic antibiotics can effectively clear catheter-related bacteraemia in children without significant late recurrence at 6 weeks. The mean infection-free survival of the catheters following TPA-antibiotic locks treatment is shorter than that following heparin–antibiotic locks treatment, but is not statistically significant synthetic construct

Organism

Organism UniProt Comment Textmining
synthetic construct
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-
-

Synonyms

Synonyms Comment Organism
Tissue plasminogen activator
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synthetic construct
tPA
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synthetic construct