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Literature summary for 3.4.21.68 extracted from
- Role of tryptophan-63 of the kringle 2 domain of tissue-type plasminogen activator in its thermal stability, folding, and ligand binding properties (1997), Biochemistry, 36, 7652-7663.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| hybridoma cell lines expressing Mabs 364, 623, 663, and 700, all directed to wtr-K2 tPA, cDNA cloning, recombinant kringle 2 domain r-K2 tPA expressed in Pichia pastoris cells | Homo sapiens |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| crystal structure of the kringle 2 domain | Homo sapiens |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 9553 | - |
MALDI-TOF-DE-MS | Homo sapiens |
| 9556 | - |
calculated from amino acid sequence | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| plasminogen + H2O | Homo sapiens | - |
plasmin + ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
human | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| plasminogen + H2O | - |
Homo sapiens | plasmin + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Tissue-type plasminogen activator | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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