Literature summary for 3.4.21.5 extracted from

Sugawara, T.; Jadhav, V.; Ayer, R.; Chen, W.; Suzuki, H.; Zhang, J.H.
Thrombin inhibition by argatroban ameliorates early brain injury and improves neurological outcomes after experimental subarachnoid hemorrhage in rats (2009), Stroke, 40, 1530-1532.

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Application

Application	Comment	Organism
medicine	thrombin inhibition by argatroban improves neurological outcomes and provides neuroprotection against acute events after subarachnoid hemorrhage such as blood-brain barrier disruption, brain edema, and cell death	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
argatroban	thrombin inhibition by argatroban improves neurological outcomes and provides neuroprotection against acute events after subarachnoid hemorrhage such as blood-brain barrier disruption, brain edema, and cell death	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Rattus norvegicus	-

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Release 2023.1 (January 2023)