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Literature summary for 3.4.21.5 extracted from
- Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin (2009), Reprod. Biol. Endocrinol., 7, 2-2.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | thrombin augments the contractility of uterine smooth muscle cell and immortalized myometrial smooth muscle cell collagen gels. The effect is inhibited by thrombin inhibitor hirudin. Thrombin-induced collagen contractility results in activation of thrombin receptor F2R | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Hirudin | - |
Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| smooth muscle | - |
Homo sapiens | - |
| uterus | - |
Homo sapiens | - |
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Release 2023.1 (January 2023)
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