Inhibitors | Comment | Organism | Structure |
---|---|---|---|
factor VIII(716-731) peptide | thrombin binding sequence is GDYYEDSYEDISAYLL, competitive | Homo sapiens | |
fibrin gamma'-peptides | sulfated and non-sulfated peptide sequences of the gamma'-chains of human fibrin 1 and 2, overview, competitive | Homo sapiens | |
fibrinogen gamma'(408-427) peptide | of the gamma'-domain, thrombin binding sequence is VRPEHPAETEYDSLYPEDDL, competitive | Homo sapiens | |
hirudin(53-64) peptide | thrombin binding sequence is NGDFEEIPEEYL, competitive | Homo sapiens | |
human GPIBalpha(269-287) peptide | thrombin binding sequence is DEGDTDLYDYYPEEDTEGD, competitive | Homo sapiens | |
human heparin cofactor II(56-75) peptide | thrombin binding sequences are GEEDDDYLDLE and EDDDYIDIVD, competitive | Homo sapiens | |
human PAR1(52-69) peptide | thrombin binding sequence is YEPFWEDEEKNESGLTEY, competitive | Homo sapiens | |
Phe-Pro-Arg-chloromethyl ketone | i.e. PPACK | Homo sapiens | |
thrombomodulin(408-426) peptide | thrombin binding sequence is GDYYEDSYEDISAYLL, competitive | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
36500 | - |
- |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
fibrinogen 1 + H2O | Homo sapiens | - |
fibrin 1 + fibrinopeptide A + fibrinopeptide B | - |
? | |
fibrinogen 2 + H2O | Homo sapiens | - |
fibrin 2 + fibrinopeptide A + fibrinopeptide B | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
fibrinogen 1 + H2O | - |
Homo sapiens | fibrin 1 + fibrinopeptide A + fibrinopeptide B | - |
? | |
fibrinogen 1 + H2O | human, composed of 2 gamma-chains, gamma A and gamma' | Homo sapiens | fibrin 1 + fibrinopeptide A + fibrinopeptide B | fibrin 1 contains a low affinity binding site in the E doamin, and a high affinity binding site at residues 408-427 of the gamma'-chain, sequence VRPEHPAETEYDSLYPEDDL, for thrombin exosites, binding study, overview | ? | |
fibrinogen 2 + H2O | - |
Homo sapiens | fibrin 2 + fibrinopeptide A + fibrinopeptide B | - |
? | |
fibrinogen 2 + H2O | human, composed of 2 gamma-chains, gamma A and gamma' | Homo sapiens | fibrin 2 + fibrinopeptide A + fibrinopeptide B | fibrin 2 contains a low affinity binding site in the E doamin, and a high affinity binding site at residues 408-427 of the gamma'-chain, sequence VRPEHPAETEYDSLYPEDDL, for thrombin exosites, binding study, overview | ? |
Synonyms | Comment | Organism |
---|---|---|
alpha-thrombin | - |
Homo sapiens |