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Literature summary for 3.4.21.4 extracted from

  • Kwong, K.; Nassenstein, C.; de Garavilla, L.; Meeker, S.; Undem, B.J.
    Thrombin and trypsin directly activate vagal C-fibres in mouse lung via protease-activated receptor-1 (2010), J. Physiol., 588, 1171-1177.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.4

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protease-activated receptor-1 + H2O Bos taurus activation ?
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protease-activated receptor-2 + H2O Bos taurus activation ?
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 ?
protease-activated receptor-3 + H2O Bos taurus activation ?
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 ?
protease-activated receptor-4 + H2O Bos taurus activation ?
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 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
protease-activated receptor-1 + H2O activation Bos taurus ?
-
 ?
protease-activated receptor-2 + H2O activation Bos taurus ?
-
 ?
protease-activated receptor-3 + H2O activation Bos taurus ?
-
 ?
protease-activated receptor-4 + H2O activation Bos taurus ?
-
 ?

General Information

General Information Comment Organism
additional information thrombin and trypsin directly activate vagal C-fibres in C57BL6 mouse lung via protease-activated receptor-1, i.e. PAR1, not via PAR3, PAR2, and PAR4, overview Bos taurus