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Literature summary for 3.4.21.4 extracted from
- Trypsin can activate the epithelial sodium channel (ENaC) in microdissected mouse distal nephron (2008), Am. J. Physiol. Renal Physiol., 295, F1052-F1062.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Soybean trypsin inhibitor | - |
Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| collecting duct | - |
Mus musculus | - |
| connecting tubule cell | - |
Mus musculus | - |
| cortical collecting duct cell | - |
Mus musculus | - |
| kidney | - |
Mus musculus | - |
| M-1 collecting duct cell | - |
Mus musculus | - |
| nephron | distal nephron | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| epithelial sodium channel + H2O | trypsin activates epithelial sodium channels in native renal tubules | Mus musculus | ? | - |
? |  |
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