Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-2266 + H2O | i.e. H-D-Val-Leu-Arg-4-nitroanilide | Mus musculus | ? | - |
? |
General Information | Comment | Organism |
---|---|---|
malfunction | partial or total deficiency in tissue kallikrein induces resistance to the infarct size reducing effect of cyclosporin A in cardiac ischemia in mice | Mus musculus |
physiological function | tissue kallikrein is required for the cardioprotective effect of cyclosporin A in myocardial ischemia in the mouse. The enzyme is required for the mitochondrial action of cyclosporin A and may interact with cyclophilin D | Mus musculus |