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Literature summary for 3.4.21.35 extracted from
- Tissue kallikrein proteolytic cascade pathways in normal physiology and cancer (2007), Biochim. Biophys. Acta, 1776, 22-31.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | allosteric inhibition | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| prostate cancer cell | - |
Homo sapiens | - |
| prostate gland | - |
Homo sapiens | - |
| prostatic fluid | - |
Homo sapiens | - |
| seminal plasma | - |
Homo sapiens | - |
| skin | - |
Homo sapiens | - |
| skin cancer cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| insulin-like growth factor binding protein + H2O | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| kallikrein-related peptidase | - |
Homo sapiens |
| KLK | - |
Homo sapiens |
| More | KLK1, KLK4, and KLK11 are serine proteases with trypsin-like activity, while KLK9 has chymotrypsin-like activity | Homo sapiens |
| PSA/KLK3 | - |
Homo sapiens |
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