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Literature summary for 3.4.21.35 extracted from

  • Del Nery, E.; Chagas, J.R.; Juliano, M.A.; Juliano, L.; Prado, E.S.
    Comparison of human and porcine tissue kallikrein substrate specificities (1999), Immunopharmacology, 45, 151-157.
    View publication on PubMed
Search for more literature for 3.4.21.35

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0002
-
 o-aminobenzoyl-FRSSR-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
0.0003
-
 o-aminobenzoyl-QPLGQTSLMKRP-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
0.00035
-
 o-aminobenzoyl-GFSPFRSVQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
0.0004
-
 o-aminobenzoyl-GFSPFRSSRQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
0.00041
-
 o-aminobenzoyl-GFSPFRSVQVMKYEGSQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
0.00051
-
 o-aminobenzoyl-GFSPFRSVQVMKYEGSQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
0.0006
-
 o-aminobenzoyl-FRSSR-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
0.00076
-
 o-aminobenzoyl-GFSPFRSSRQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
0.0009
-
 o-aminobenzoyl-FRSVQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
0.0014
-
 o-aminobenzoyl-GFSPFRSVQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
0.0023
-
 o-aminobenzoyl-LMKRP-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
0.0039
-
 o-aminobenzoyl-QPLGMISLMKRP-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
0.0042
-
 o-aminobenzoyl-QPLGMISLMKRP-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
0.0047
-
 o-aminobenzoyl-LMKRP-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
0.0067
-
 o-aminobenzoyl-GFSPFRSSRIGEIKEEQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
0.0073
-
 o-aminobenzoyl-FRSVQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
0.0104
-
 o-aminobenzoyl-GFSPFRSSRIGEIKEEQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
0.0455
-
 o-aminobenzoyl-QPLGQTSLMKRP-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
polypeptide + H2O Homo sapiens
-
 peptides
-
 ?
polypeptide + H2O Sus scrofa
-
 peptides
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Sus scrofa
-
 form B
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information substrate specificity study Homo sapiens ?
-
 ?
additional information substrate specificity study Sus scrofa ?
-
 ?
o-aminobenzoyl-FRSSR-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Arg-Ser bond in human kininogen Homo sapiens o-aminobenzoyl-FR + SSR-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-FRSSR-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Arg-Ser bond in human kininogen Sus scrofa o-aminobenzoyl-FR + SSR-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-FRSVQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Arg-Ser bond in bovine kininogen Homo sapiens o-aminobenzoyl-FR + SVQ-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-FRSVQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Arg-Ser bond in bovine kininogen Sus scrofa o-aminobenzoyl-FR + SVQ-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-GFSPFRSSRIGEIKEEQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Arg-Ser bond in human kininogen Homo sapiens o-aminobenzoyl-GFSPFR + SSRIGEIKEEQ-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-GFSPFRSSRIGEIKEEQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Arg-Ser bond in human kininogen Sus scrofa o-aminobenzoyl-GFSPFR + SSRIGEIKEEQ-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-GFSPFRSSRQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Arg-Ser bond in human kininogen Homo sapiens o-aminobenzoyl-GFSPFR + SSRQ-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-GFSPFRSSRQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Arg-Ser bond in human kininogen Sus scrofa o-aminobenzoyl-GFSPFR + SSRQ-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-GFSPFRSVQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Arg-Ser bond in bovine kininogen Homo sapiens o-aminobenzoyl-GFSPFR + SVQ-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-GFSPFRSVQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Arg-Ser bond in bovine kininogen Sus scrofa o-aminobenzoyl-GFSPFR + SVQ-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-GFSPFRSVQVMKYEGSQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Arg-Ser bond in bovine kininogen Homo sapiens o-aminobenzoyl-GFSPFR + SVQVMKYEGSQ-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-GFSPFRSVQVMKYEGSQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Arg-Ser bond in bovine kininogen Sus scrofa o-aminobenzoyl-GFSPFR + SVQVMKYEGSQ-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-LMKRP-N-(2,4-dinitrophenyl)ethylene diamine + H2O low activity Homo sapiens o-aminobenzoyl-LM + KRP-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-LMKRP-N-(2,4-dinitrophenyl)ethylene diamine + H2O low activity Sus scrofa o-aminobenzoyl-LM + KRP-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-LMKRP-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Met-Lys bond in human and bovine kininogen Homo sapiens o-aminobenzoyl-LM + KRP-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-QPLGMISLMKRP-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Met-Lys bond in human kininogen Homo sapiens o-aminobenzoyl-QPLGMISLM + KRP-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-QPLGMISLMKRP-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Met-Lys bond in human kininogen Sus scrofa o-aminobenzoyl-QPLGMISLM + KRP-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-QPLGQTSLMKRP-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Met-Lys bond in bovine kininogen Homo sapiens o-aminobenzoyl-QPLGQTSLM + KRP-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-QPLGQTSLMKRP-N-(2,4-dinitrophenyl)ethylene diamine + H2O sequence spanning the scissile Met-Lys bond in bovine kininogen Sus scrofa o-aminobenzoyl-QPLGQTSLM + KRP-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
polypeptide + H2O
-
 Homo sapiens peptides
-
 ?
polypeptide + H2O
-
 Sus scrofa peptides
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.04
-
 o-aminobenzoyl-LMKRP-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
0.076
-
 o-aminobenzoyl-LMKRP-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
0.4
-
 o-aminobenzoyl-QPLGMISLMKRP-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
0.6
-
 o-aminobenzoyl-QPLGQTSLMKRP-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
0.9
-
 o-aminobenzoyl-FRSVQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
0.94
-
 o-aminobenzoyl-GFSPFRSVQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
1
-
 o-aminobenzoyl-GFSPFRSSRQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
1.1
-
 o-aminobenzoyl-QPLGQTSLMKRP-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
1.4
-
 o-aminobenzoyl-FRSSR-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
1.5
-
 o-aminobenzoyl-GFSPFRSVQVMKYEGSQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
1.6
-
 o-aminobenzoyl-FRSVQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
3
-
 o-aminobenzoyl-GFSPFRSSRIGEIKEEQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
3.1
-
 o-aminobenzoyl-GFSPFRSSRIGEIKEEQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
4
-
 o-aminobenzoyl-GFSPFRSVQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
7
-
 o-aminobenzoyl-FRSSR-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa
7.1
-
 o-aminobenzoyl-QPLGMISLMKRP-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
7.5
-
 o-aminobenzoyl-GFSPFRSSRQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Homo sapiens
40.1
-
 o-aminobenzoyl-GFSPFRSVQVMKYEGSQ-N-(2,4-dinitrophenyl)ethylene diamine pH 9.0, 30°C Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9
-
 assay at Homo sapiens
9
-
 assay at Sus scrofa