Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.35 extracted from

  • Blaber, M.; Isackson, P.J.; Marsters, J.C.; Burnier, J.P.; Bradshaw, R.A.
    Substrate specificities of growth factor associated kallikreins of the mouse submandibular gland (1989), Biochemistry, 28, 7813-7819.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Zn2+
-
Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0183
-
D-Val-Leu-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
0.02
-
Ala-Arg-Arg-4-methylcoumarin 7-amide
-
Sus scrofa
0.222
-
acetyl-Ala-Leu-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
0.291
-
acetyl-Glu-Lys-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
0.383
-
N-alpha-acetyl-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
0.571
-
acetyl-Ala-Thr-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
0.765
-
acetyl-Glu-Phe-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
0.849
-
acetyl-Glu-Leu-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
0.868
-
D-Val-Leu-Lys-4-nitroanilide pH 8.5, 37°C Sus scrofa
0.929
-
acetyl-Glu-Thr-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
polypeptide + H2O Sus scrofa
-
peptides
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
Sus scrofa
-
submandibular gland
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-Ala-Leu-Arg-p-nitroanilide + H2O
-
Sus scrofa acetyl-Ala-Leu-Arg + p-nitroaniline
-
?
acetyl-Ala-Thr-Arg-p-nitroanilide + H2O
-
Sus scrofa acetyl-Ala-Thr-Arg + p-nitroaniline
-
?
acetyl-Arg-p-nitroanilide + H2O
-
Sus scrofa acetyl-Arg + p-nitroaniline
-
?
acetyl-Glu-Leu-Arg-p-nitroanilide + H2O
-
Sus scrofa acetyl-Glu-Leu-Arg + p-nitroaniline
-
?
acetyl-Glu-Lys-Arg-p-nitroanilide + H2O
-
Sus scrofa acetyl-Glu-Lys-Arg + p-nitroaniline
-
?
acetyl-Glu-Phe-Arg-p-nitroanilide + H2O
-
Sus scrofa acetyl-Glu-Phe-Arg + p-nitroaniline
-
?
acetyl-Glu-Thr-Arg-p-nitroanilide + H2O
-
Sus scrofa acetyl-Glu-Thr-Arg + p-nitroaniline
-
?
Ala-Arg-Arg-7-amido-4-methylcoumarin + H2O
-
Sus scrofa Ala-Arg-Arg + 7-amino-4-methylcoumarin
-
?
benzyloxycarbonyl-Arg-p-nitroanilide + H2O
-
Sus scrofa benzyloxycarbonyl-Arg + p-nitroaniline
-
?
D-Val-Leu-Arg-p-nitroanilide + H2O
-
Sus scrofa D-Val-Leu-Arg + p-nitroaniline
-
?
D-Val-Leu-Lys-4-nitroanilide + H2O
-
Sus scrofa D-Val-Leu-Lys + 4-nitroaniline
-
?
polypeptide + H2O
-
Sus scrofa peptides
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Sus scrofa

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.029
-
acetyl-Glu-Lys-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
0.154
-
N-alpha-acetyl-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
0.38
-
acetyl-Glu-Thr-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
0.72
-
acetyl-Ala-Thr-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
4.1
-
D-Val-Leu-Lys-4-nitroanilide pH 8.5, 37°C Sus scrofa
6.6
-
D-Val-Leu-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
6.62
-
acetyl-Glu-Phe-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
6.74
-
acetyl-Ala-Leu-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa
9.2
-
acetyl-Glu-Leu-Arg-p-nitroanilide pH 8.5, 37°C Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
assay at Sus scrofa