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Literature summary for 3.4.21.35 extracted from

  • Webster, M.E.; Prado, E.S.
    Glandular kallikreins from horse and human urine and from hog pancreas (1970), Methods Enzymol., 19, 681-699.
No PubMed abstract available
Search for more literature for 3.4.21.35

Inhibitors

Inhibitors Comment Organism Structure
benzamidine
-
 Equus caballus
benzamidine
-
 Homo sapiens
benzamidine
-
 Sus scrofa
Co2+
-
 Sus scrofa
Cu2+
-
 Sus scrofa
diisopropyl fluorophosphate
-
 Equus caballus
diisopropyl fluorophosphate
-
 Homo sapiens
diisopropyl fluorophosphate
-
 Sus scrofa
Egg white
-
 Homo sapiens
Hg2+
-
 Sus scrofa
Mn2+
-
 Sus scrofa
Ni2+
-
 Sus scrofa
pancratic inhibitor
-
 Sus scrofa
Trasylol
-
 Equus caballus
Trasylol
-
 Homo sapiens
Trasylol
-
 Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular secretion Homo sapiens
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ Na+, K+, Li+, Rb+ or Ca2+ required for activation Equus caballus
K+ Na+, K+, Li+, Rb+ or Ca2+ required for activation Equus caballus
Li+ Na+, K+, Li+, Rb+ or Ca2+ required for activation Equus caballus
Na+
-
 Homo sapiens
Na+ Na+, K+, Li+, Rb+ or Ca2+ required for activation Equus caballus
Rb+ Na+, K+, Li+, Rb+ or Ca2+ required for activation Equus caballus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
25200
-
 equilibrium sedimentation Sus scrofa
40500
-
 short column equilibrium sedimentation Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
polypeptide + H2O Homo sapiens
-
 peptides
-
 ?
polypeptide + H2O Sus scrofa
-
 peptides
-
 ?
polypeptide + H2O Equus caballus
-
 peptides
-
 ?

Organism

Organism UniProt Comment Textmining
Equus caballus
-
-
-
Homo sapiens
-
-
-
Sus scrofa
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
side-chain modification
-
 Homo sapiens
side-chain modification the glycoprotein consists of 283 amino acid residues and 19-21 sugar residues Sus scrofa

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens
-
 Sus scrofa
-
 Equus caballus

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
 Homo sapiens
-
pancreas
-
 Sus scrofa
-
urine
-
 Homo sapiens
-
urine
-
 Equus caballus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
kininogen + H2O
-
 Homo sapiens kinin + ?
-
 ?
kininogen + H2O
-
 Sus scrofa kinin + ?
-
 ?
kininogen + H2O
-
 Equus caballus kinin + ?
-
 ?
low-molecular-weight kininogen + H2O
-
 Homo sapiens kallidin + kinin
-
 ?
low-molecular-weight kininogen + H2O
-
 Sus scrofa kallidin + kinin
-
 ?
low-molecular-weight kininogen + H2O
-
 Equus caballus kallidin + kinin
-
 ?
poly-L-Arg + H2O
-
 Equus caballus ?
-
 ?
polypeptide + H2O
-
 Homo sapiens peptides
-
 ?
polypeptide + H2O
-
 Sus scrofa peptides
-
 ?
polypeptide + H2O
-
 Equus caballus peptides
-
 ?
salmine + H2O
-
 Equus caballus ?
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
20
-
 pH 7.0-9.5, 5 h, stable. Little loss of activity after 5 h at pH 4.4 Sus scrofa