Protein Variants | Comment | Organism |
---|---|---|
K192E | completely ineffective mutant enzyme | Homo sapiens |
K192Q | mutant has 44% of the activity compared to the wild-type enzyme | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Bovine pancreatic trypsin inhibitor | mutant enzyme K192E is poorly inhibited, mutant enzyme K192Q is inhibited more than the wild-type enzyme | Homo sapiens | |
tissue factor pathway inhibitor | no inhibition of the mutant enzymes K192E and K192Q | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
chromozym t-PA + H2O | - |
Homo sapiens | ? | - |
? | |
D-cyclohexylglycyl-L-2-aminobutyryl-L-arginyl-4-nitroanilide + H2O | - |
Homo sapiens | D-cyclohexylglycyl-L-2-aminobutyryl-L-arginine + 4-nitroaniline | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | turnover-number of wild-type and mutant enzymes | Homo sapiens |