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Literature summary for 3.4.21.21 extracted from
- The esterase activity of coagulation factor VII. Evidence for intrinsic activity of the zymogen (1978), J. Biol. Chem., 253, 2203-2209.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| benzamidine HCl | - |
Bos taurus |  |
| diisopropylfluorophosphate | - |
Bos taurus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.19 | - |
benzyloxycarbonyl-Arg-p-nitrobenzyl ester | - |
Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| proteolytic modification | the activated two-chain enzyme factor VIIa is formed from the single chain zymogen factor VII | Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzyloxycarbonyl-Arg-p-nitrobenzyl ester + H2O | - |
Bos taurus | benzyloxycarbonyl-Arg + 4-nitrophenyl | - |
? | |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.8 | - |
benzyloxycarbonyl-Arg-p-nitrobenzyl ester | - |
Bos taurus | |
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Release 2023.1 (January 2023)
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