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Literature summary for 3.4.21.21 extracted from

  • Seested, T.; Appa, R.S.; Christensen, E.I.; Ioannou, Y.A.; Krogh, T.N.; Karpf, D.M.; Nielsen, H.M.
    In vivo clearance and metabolism of recombinant activated factor VII (rFVIIa) and its complexes with plasma protease inhibitors in the liver (2011), Thromb. Res., 127, 356-362.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Synonyms

Synonyms Comment Organism
factor VIIa
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Homo sapiens
FVIIa
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Homo sapiens
NovoSeven commercial preparation Homo sapiens

General Information

General Information Comment Organism
physiological function following injection in mice, both hepatocytes and Kupffer cells appear to be involved in the hepatic clearance and metabolism of both full-length recombinant factor VIIa and recombinant factor VIIa in complex with at least two plasma protease inhibitors Homo sapiens