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BRENDA support

Literature summary for 3.4.21.21 extracted from

  • Pinotti, M.; Balestra, D.; Rizzotto, L.; Maestri, I.; Pagani, F.; Bernardi, F.
    Rescue of coagulation factor VII function by the U1+5A snRNA (2009), Blood, 113, 6461-6464.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
factor X + H2O
-
Mus musculus factor Xa
-
?

Synonyms

Synonyms Comment Organism
factor VIIa
-
Mus musculus

General Information

General Information Comment Organism
malfunction the small nuclear RNA-U1 (U1+ 5a) mediated rescue of FVII mRNA processing impaired by the 9726 + 5G to A mutation results in an appreciable secretion of functional FVII Mus musculus