Activating Compound | Comment | Organism | Structure |
---|---|---|---|
vitamin K | dependent on | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | Ca2+ and the Gla domain are required for membrane binding by the enzyme, mechanism of Ca2+-mediated binding, molecular dynamics simulation of complex formation, overview | Homo sapiens | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | dependent on, eight Ca2+ are bound via the Gla domain and involved in enzyme binding to the membrane with different tasks, structure and coordination, mechanism of Ca2+-mediated binding, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | membrane binding constitutes a key process in enzymatic activation of various blood coagulation factors | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | membrane binding constitutes a key process in enzymatic activation of various blood coagulation factors | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | Ca2+ and the Gla domain are required for membrane binding by the enzyme involving residues R9, R15, K18, R28, K32, R36, and K38, molecular dynamics simulation of complex formation, structure, overview | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
FVIIa | - |
Homo sapiens |