Activating Compound | Comment | Organism | Structure |
---|---|---|---|
hepatocyte growth factor activator inhibitor | HAI-1, zymogen activator of matriptase | Homo sapiens | |
additional information | controlled by a serpin complex, consisting of antithrombin III, alpha1-antitrypsin and alpha2-antiplasmin | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
hepatocyte growth factor activator inhibitor | HAI-1, conventional protease inhibitor | Homo sapiens | |
additional information | controlled by a serpin complex, consisting of antithrombin III, alpha1-antitrypsin and alpha2-antiplasmin | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
25000 | - |
serine protease domain, identified by SDS-PAGE, Western blot analysis and LC-MS,MS, without serpin complex | Homo sapiens |
45000 | - |
noncatalytic domain, identified by SDS-PAGE, Western blot analysis and LC-MS,MS | Homo sapiens |
80000 | - |
serine protease domain, identified by SDS-PAGE, Western blot analysis and LC-MS,MS, including serpin complex | Homo sapiens |
110000 | - |
matripase complex | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y5Y6 | - |
- |
Purification (Comment) | Organism |
---|---|
from human milk using a CM-Sepharose FF column and a HAI-1 immunoaffinity column | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast cancer cell | - |
Homo sapiens | - |
carcinoma cell | - |
Homo sapiens | - |
epithelial cell | - |
Homo sapiens | - |
macrophage | - |
Homo sapiens | - |
mammary epithelial cell line | - |
Homo sapiens | - |
milk | - |
Homo sapiens | - |
monocyte | - |
Homo sapiens | - |
ovary cancer cell line | - |
Homo sapiens | - |
Subunits | Comment | Organism |
---|---|---|
heteromer | noncatalytic domain 45 kDa, serine protease domain 25 kDa, serpins 55 kDa | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
epithin | - |
Homo sapiens |
matriptase | - |
Homo sapiens |
MT-SP1 | - |
Homo sapiens |
ST-14 | - |
Homo sapiens |
TADG15 | - |
Homo sapiens |
type 2 transmembrane serine protease | - |
Homo sapiens |