Application | Comment | Organism |
---|---|---|
additional information | resistance to degradation and stabilization of beta1-6GlcNAc matripase are specifically due to the presence of beta1-6GlcNAc branching on the sugar chains, binds strongly to leukoagglutinating phytohemagglutinin, which preferentially recognizes beta1-6 GlcNAc branches of tri- or tetraantennary sugar chains, beta1-6 GlcNAc matriptase is resistant to autodegradation, as well as trypsin digestion, compared with matriptase purified from mock-transfected cells, N-glycosidase-F treatment of beta1-6 GlcNAc matriptase greatly reduces its resistance to degradation | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
N302Q | significant resistance to degradation in the N-acetylglucosminyltransferase V transfectants | Homo sapiens |
N485Q | significant resistance to degradation in the N-acetylglucosminyltransferase V transfectants | Homo sapiens |
N772Q | completely degraded in the N-acetylglucosminyltransferase V transfectants | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
from N-acetylglucosminyltransferase V transfectant by immunoaffinity chromatography | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MKN-45 cell | - |
Homo sapiens | - |
additional information | COS cell | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gelatin + H2O | - |
Homo sapiens | ? | - |
? | |
N-Ala-Ala-Ala-Tyr-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | ? | - |
? | |
N-succinyl-Ala-Phe-Lys-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | ? | - |
? | |
N-succinyl-Leu-Leu-Val-Tyr-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | ? | - |
? | |
N-tert-butoxycarbonyl-gamma-benzyl-Glu-Ala-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | ? | - |
? | |
N-tert-butoxycarbonyl-Gln-Ala-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | ? | - |
? |