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Literature summary for 3.4.21.109 extracted from

  • Enyedy, I.J.; Lee, S.L.; Kuo, A.H.; Dickson, R.B.; Lin, C.Y.; Wang, S.
    Structure-based approach for the discovery of bis-benzamidines as novel inhibitors of matriptase (2001), J. Med. Chem., 44, 1349-1355.
    View publication on PubMed
Search for more literature for 3.4.21.109

Inhibitors

Inhibitors Comment Organism Structure
hexamidine and its structural analogs Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens degrades extracellular matrix ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9Y5Y6
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information degrades extracellular matrix Homo sapiens ?
-
 ?
N-tert-butoxycarbonyl-Gln-Ala-Arg-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens N-tert-butoxycarbonyl-Gln-Ala-Arg + 7-amino-4-methylcoumarin
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000924
-
 hexamidine pH 8.5 Homo sapiens