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Literature summary for 3.4.21.109 extracted from

  • Takeuchi, T.; Harris, J.L.; Huang, W.; Yan, K.W.; Coughlin, S.R.; Craik, C.S.
    Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates (2000), J. Biol. Chem., 275, 26333-26342.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Homo sapiens 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
80000
-
SDS-PAGE, recombinant protease domain Homo sapiens
85000
-
SDS-PAGE, full length enzyme Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
Homo sapiens
-
PC-3 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Arg-Xaa-Ser-Arg-Ala + H2O X: non-basic amino acid, good substrate Homo sapiens Arg-Xaa-Ser + Arg-Ala
-
?
Lys-Xaa-Ser-Arg-Ala + H2O X: non-basic amino acid, good substrate Homo sapiens Lys-Xaa-Ser + Arg-Ala
-
?
additional information preferred amino acid residues: at P4 position: Lys and Arg, at P3 position: basic residues and Glu, at P2 position: Gly, Ser and Phe Homo sapiens ?
-
?
single-chain urokinase-type plaminogen activator + H2O is activated by matriptase Homo sapiens ?
-
?
Xaa-Arg-Ser-Arg-Ala + H2O X: non-basic amino acid, good substrate Homo sapiens Xaa-Arg-Ser + Arg-Ala
-
?
Xaa-Lys-Ser-Arg-Ala + H2O X: non-basic amino acid, good substrate Homo sapiens Xaa-Lys-Ser + Arg-Ala
-
?

Synonyms

Synonyms Comment Organism
membrane-type serine protease 1
-
Homo sapiens
MT-SP-1
-
Homo sapiens