Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
PARL | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | 16 SNPs are identified in 1086 Caucasian individuals. Statistical genetic analysis reveal that one promoter variant, T-191C, exhibit significant effects on mitochondrial content levels. Comparison of the transcription factor binding characteristics of the T-191C promoter SNP by EMSA indicates preferential binding of nuclear factors to the T allele, suggesting functional variation in PARL expression | Homo sapiens |