Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
PARL | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | muscle knockdown of PARL in mice results in malformed mitochondrial cristae, lower mitochondrial content, decreased PGC1alpha protein levels, and impaired insulin signaling. Suppression of PARL protein in healthy myotubes lowers mitochondrial mass and insulin-stimulated glycogen synthesis and increases reactive oxygen species production | Mus musculus |