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BRENDA support

Literature summary for 3.4.21.10 extracted from

  • Furlong, L.I.; Harris, J.D.; Vazquez-Levin, M.H.
    Binding of recombinant human proacrosin/acrosin to zona pellucida (ZP) glycoproteins. I. Studies with recombinant human ZPA, ZPB, and ZPC (2005), Fertil. Steril., 83, 1780-1790.
    View publication on PubMed

Application

Application Comment Organism
medicine sperm-egg interaction: interaction of protein with zona pellucida glycoproteins, highest binding activity with glycoprotein ZPA. Interaction involves mannosyl, fucosyl, and sulfated glycans. Binding sites are located both on N- and C-terminus of proacrosin, revealing a key role of proenzyme in the interaction Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
recombinant protein
-

Source Tissue

Source Tissue Comment Organism Textmining
semen
-
Homo sapiens
-

Subunits

Subunits Comment Organism
More interaction of protein with zona pellucida glycoproteins, highest binding activity toward glycoprotein ZPA Homo sapiens