Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | inhibitory activity of the urea compounds synthesized depends upon the position of the methyl group at the phenyl ring and the presence of substituents at the nitrogen of the urea bridge. The inhibitory trend suggests that alpha-chymotrypsin inhibitory activity declines with ortho, meta, para substitution order | Bos taurus | |
N-(2-acetylphenyl)-N'-(3-methylphenyl) urea | - |
Bos taurus | |
N-(2-methylphenyl)-2-oxo-1-pyrrolidine carboxamide | most active inhibitor | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | P00766 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Bos taurus | - |
pancreas | - |
Bos taurus | - |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00824 | - |
pH 7.6, 25°C | Bos taurus | N-(2-methylphenyl)-2-oxo-1-pyrrolidine carboxamide | |
0.0136 | - |
pH 7.6, 25°C | Bos taurus | N-(2-acetylphenyl)-N'-(3-methylphenyl) urea |