Any feedback?
Literature summary for 3.4.21.1 extracted from
- A dimeric high-molecular-weight chymotrypsin inhibitor with antitumor and HIV-1 reverse transcriptase inhibitory activities from seeds of Acacia confusa (2010), Phytomedicine, 17, 621-625.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Acacia confusa chymotrypsin inhibitor | large, dimeric 70 kDa chymotrypsin inhibitor with a molar ratio of inhibition between the chymotrypsin inhibitor and alpha-chymotrypsin of 2:1, which gives about 100% inhibition. The molar ratio of chymotrypsin inhibitor to chymotrypsin is usually 1:1. Its chymotrypsin inhibitory activity is stable from pH 3-10 and from 0-50°C. Exerts antiproliferative activity toward breast cancer MCF-7 cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| MCF-7 cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alpha-chymotrypsin | - |
Homo sapiens |
| chymotrypsin | - |
Homo sapiens |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.008 | - |
- |
Homo sapiens | Acacia confusa chymotrypsin inhibitor |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
