Application | Comment | Organism |
---|---|---|
drug development | winged bean chymotrypsin-trypsin inhibitor is a dual inhibitor of both chymotrypsin and trypsin and a promising candidate to study for its insecticidal properties against Helicoverpa armigera and other insect pests | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
winged bean chymotrypsin-trypsin inhibitor | inhibitor from Psophocarpus tetragonolobus, inhibits and binds trypsin and chymotrypsin in a 1:1 molar ratio. Complete inhibition of chymotrypsin with purified recombinant inhibitor at a 1:1 molar ratio, similarly to the inhibitor obtained from winged bean seeds | Bos taurus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
additional information | - |
43000, recombinant winged bean chymotrypsin-trypsin inhibitor in complex with chymotrypsin, gel filtration | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-benzoyl-L-Tyr ethyl ester + H2O | - |
Bos taurus | N-benzoyl-L-Tyr + ethanol | - |
? |
Synonyms | Comment | Organism |
---|---|---|
chymotrypsin | - |
Bos taurus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00000188 | - |
winged bean chymotrypsin-trypsin inhibitor | Dixon plot analysis, same for recombinant inhibitor and inhibitor obtained from winged bean seeds | Bos taurus |